Modern regenerative medicine harnesses the power of growth factors to revolutionize the way healthcare and cosmetic treatments work. One of the most recent entries in this scenario is Endoret PRGF, which uses a higher concentration of autologous growth factors to promote quicker tissue repair and regeneration. This technology is known for promoting cell proliferation at a higher rate. It has been found effective in various applications, including hair regrowth, wound and ulcer treatment, and aesthetic improvement.
At Dubai Cosmetic Surgery Clinic, our practitioners have specialized training to administer Endoret PRGF treatment according to set protocols. We adhere to the latest advancements in regenerative medicine to help you achieve your cosmetic and healthcare goals.
What is Endoret PRGF?
Endoret PRGF is a closed system that uses specialized equipment—consisting of unitary and disposable kits—for the preparation of autologous growth factors in a sterile condition. It involves isolating, concentrating, and extracting growth factors from the patient’s own blood to prepare the PRGF (Plasma rich in growth factors) solution. This solution is then used topically or subcutaneously, depending on the treatment goals.
How is Endoret PRGF Made?
Endoret PRGF is prepared using the Endoret (Endogenous Regenerative Technology) system. It is a multi-step protocol to prepare a highly concentrated PRGF formulation from the patient’s blood. The process usually involves the following steps:
- Blood extraction: In the first step, the practitioner extracts a sample of blood from the patient’s vein.
- Centrifugation: The blood sample is placed in a centrifuge device, which spins it at a high RPM to separate red and white blood cells from growth factor-rich plasma. The plasma is then drawn out.
- Growth factor activation: In this step, the practitioner adds calcium chloride to the plasma to activate the release of growth factors, such as EGF, VEGF, TGF-ß1, PDGF-AB, and FGF. These growth factors promote cell proliferation, leading to tissue regeneration in the treated area.
- Forming PRGF-Endoret: The formulation is processed further to create the final PRGF-Endoret product, which can be a liquid solution, fibrin membrane, or 3D fibrin scaffold, depending on the treatment requirements.
What is PRGF-Endoret Used For?
Doctors and cosmeticians use PRGF-Endoret for various purposes. The most common applications of this product include the following:
- PRGF-Endoret Facial Rejuvenation: Plasma Rich in Growth Factors promotes tissue regeneration by accelerating the production of fibroblasts and restructuring the collagen matrix. This helps reduce fine lines and wrinkles and improve hydration. Practitioners often use the mesotherapy technique to administer PRGF to the facial skin. When combined with Fractional CO2 laser therapy, this technique may also help reduce the appearance of acne scars.
- PRGF-Endoret for Hair Loss: PRGF may help treat androgenic alopecia (pattern baldness) by supporting follicular activity in the scalp. During the treatment, the practitioner injects the PRGF-Endoret solution into the scalp using very fine, short needles. Once injected, this solution stimulates the formation of new blood vessels, potentially reinstating the follicles’ Anagen (growth) phase.
- PRGF-Endoret for Wounds and Ulcers: This treatment usually involves two steps. First, the practitioner injects the activated PRGF solution around the wound or ulcer site. Then, they apply the Endoret Fibrin Clot, which is in a gel form, directly to the wound. Both the injected solution and Fibrin Clot work to clear the affected area of dead skin cells, bacteria, and broken extracellular matrix while promoting clot formation and collagen restructuring. As a result, the wound-healing process (cicatrization) is accelerated.
What Are the Results of PRGF Endoret Treatment?
The result expectancy of PRGF Endoret depends significantly on its application and other individual factors.
Generally, initial treatment results are visible in the first 1-3 weeks, while full results may take up to six months to appear. The exact timeline can vary depending on the treatment type. For instance, the results of wound/ulcer treatment are quicker than those of skin rejuvenation/aesthetic treatment. For more specific details about results, please consult your practitioner.
Benefits of PRGF Treatment
The most salient benefits of PRGF treatment are as follows:
- Improved healing with a lower risk of infection
- Improved soft tissue regeneration and repair
- Biocompatible treatment with a lower risk of side effects
Endoret Treatment FAQ’s
How Many Sessions of PRGF Endoret Treatment Are Needed?
Your doctor may recommend 3-6 sessions of PRGF-Endoret, which are usually one month apart. The exact treatment plan will depend on your treatment goals or requirements.
What are Endoret Treatment Aftercare
PRGF Endoret is a minimally invasive treatment that usually requires no extensive aftercare instructions. You may resume your routine activities right after the procedure.
That being said, you may need to use local icing to reduce swelling and discomfort caused by injection needles. Moreover, your doctor may ask you to avoid NSAIDs and herbal supplements to prevent blood thinning, especially when you have undergone wound/ulcer treatment.
What Are The Side Effects of PRGF Endoret Treatment?
Endoret PRGF is generally considered safe with little to no risk of severe side effects. The injection-based PRGF treatment may cause bruising and discomfort in the treated region. These side effects usually subside in a few days.
What is the Difference between PRGF and PRP?
To be precise, PRGF is the final product of PRP. In its raw form, PRP contains leukocytes and inflammatory cytokines, which can prove counterproductive for tissue regeneration. The PRGF solution, on the other hand, contains growth factors in a higher concentration and only a specific amount of cytokines. With this more refined composition, PRGF causes less pain and swelling and is considered more effective than PRP.
Book a Consultation
At Dubai Cosmetic Surgery Clinic, we offer PRGF Endoret treatment from the hands of highly qualified, trained professionals with specialized expertise in regenerative medicine. For details, dial +971 4 348 5575. Alternatively, you can fill out the form below to book an appointment online.